John 10:17

Therefore doth my Father love me - As I shall be shortly crucified by you, do not imagine that I am abandoned by my heavenly Father, and therefore fall thus into your hands. The Father loveth me particularly on this account, because I am going to lay down my life for the life of the world. Again, do not suppose that I shall be put to death by your rulers, because I have not strength to resist them. I Lay Down my life voluntarily and cheerfully; no one can take it away from me, see John 10:18; and I shall give you the fullest proof of my supreme power by raising, in three days, that very crucified, wounded body from the grave.

I lay down my life - I give myself to die for my people, in Jewish and pagan lands. I offer myself a sacrifice to show the willingness of my Father to save them; to provide an atonement, and thus to open the way for their salvation. This proves that the salvation of man was an object dear to God, and that it was a source of special gratification to him that his Son was willing to lay down his life to accomplish his great purposes of benevolence.

That I might take it again - Be raised up from the dead, and glorified, and still carry on the work of redemption. See this same sentiment sublimely expressed in Philippians 2:5-11.

10:17 I lay down my life that I may take it again - I cheerfully die to expiate the sins of men, to the end I may rise again for their justification.