2-timothy 1:16

The Lord give mercy - Onesiphorus had acknowledged him, and continued to do so; he, and his house, or family, ministered to him in prison, and were not ashamed of their imprisoned pastor, nor of the cause for which he was in disgrace and suffering. As he showed mercy to the apostle, the apostle prays the Lord to show mercy to him.

The Lord give mercy unto the house of Onesiphorus - The family of Onesiphorus - for so the word house is often used. He was himself still living 2 Timothy 1:18, but not improbably then absent from his home; compare the notes at 2 Timothy 4:19. He was evidently of Asia, and is the only one who is mentioned from that region who had showed the apostle kindness in his trials. He is mentioned only in this Epistle, and nothing more is known of him. The record is entirely honorable to him, and for his family the apostle felt a warm interest on account of the kindness which he had showed to him in prison. The ecclesiastical traditions also state that he was one of the seventy disciples, and was ultimately Bishop of Corone. But there is no evidence of this. There is much force in the remark of the Editor of the Pictorial Bible, that "the pretended lists of the 70 disciples seem to have been made out on the principle of including all the names incidentally mentioned in the sacred books, and not otherwise appropriated."

For he oft refreshed me - That is, showed me kindness, and ministered to my needs.

And was not ashamed of my chain - Was not ashamed to be known as a friend of one who was a prisoner on account of religion. Paul was bound with a chain when a prisoner at Rome; Philippians 1:13-14, Philippians 1:16; Colossians 4:3, Colossians 4:18; Plm 1:10; see the notes at Acts 28:20.

1:16 The family of Onesiphorus - As well as himself. Hath often refreshed me - Both at Ephesus and Rome.